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Electrical Stimulation for Immune Modulation in Cancer Treatments – Click Here

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Klotho suppresses colorectal cancer through modulation of the unfolded protein response – Click Here

Klotho gene against aging and cancer. Top cancer expert – on new therapy – Click Here

Natural killer cells, T cells, and neutrophils are recruited upon SDF-1 secretion – Click Here

Bioelectric Control of Metastasis in Solid Tumors – Click Here

[PDF]Bioelectric Applications for Treatment of Melanoma – Semantic Scholar

by SJ Beebe – ‎Cited by 16 – ‎Related articles

Sep 27, 2010 – Abstract: Two new cancer therapies apply bioelectric principles. These methods target ….. voltage, high frequency cables can be used in the design together with fast semiconductor switches. ….. which is the focus of bioelectric approaches to cancer treatment, has been used for over a quarter of a century to …

[PDF]Bioelectromagnetic Field Effects on Cancer Cells and … – ResearchGate

Aug 5, 2011 – amplitude range on cancer cells and on mice bearing tumors. In contrast to invasive electrochemotherapy and electrogenetherapy, using mostly needle electrodes and single high-amplitude electropulses for treatment, extremely low- frequency (ELF) pulsating electromagnetic fields (PEMF) and sinusoidal 

The Bioelectrical Interplay Between Inflammation and Cancer. | UA …

The Bioelectrical Interplay Between Inflammation and Cancer. It is believed that fundamentally cancer is caused by genetic mutations in an individual cell which …

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Interplay between Inflammation and Stemness in Cancer Cells: The …

by DW Yeh – ‎2016 – ‎Cited by 2 – ‎Related articles

Dec 5, 2016 – Thus, the activation of TLR signaling by extrinsic and intrinsic factors drives a positiveinterplay between inflammation and stemness in cancer ..

Targeted treatment of cancer with radiofrequency electromagnetic …

by JW Zimmerman – ‎2013 – ‎Cited by 29 – ‎Related articles

Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies. Jacquelyn W. Zimmerman …. This approach is based on the use of short electric pulses inducing either irreversible or reversible changes in cell membrane permeabilization. Irreversible changes lead …

 
Intrabuccal administration of 27.12 MHz radiofrequency (RF) electromagnetic fields (EMF), which are amplitude-modulated at tumor-specific frequencies, results in long-term objective responses in patients with cancer and is not associated with any significant adverse effects.
 
This novel targeted treatment approach is emerging as an appealing therapeutic option for patients with advanced cancer given its excellent tolerability. Dissection of the molecular mechanisms accounting for the anti-cancer effects of tumor-specific modulation frequencies is likely to lead to the discovery of novel pathways in cancer.

Preclinical Study of Locoregional Therapy of Hepatocellular …

by X Chen – ‎2015 – ‎Cited by 14 – ‎Related articles

Apr 30, 2015 – Bioelectric tumor therapies produce electrical stimuli on tumor cells. The commonly used method is the pulsed electric fields. The pulsed electric filed in microsecond can perforate the cell membrane reversibly and enhance the delivery of chemotherapeutic drugs (electroporation). The electrochemotherapy …

Electrotherapy on Cancer: Experiment and Mathematical … – IntechOpen

cdn.intechopen.com/…/InTech-Electrotherapy_on_cancer_experiment_and_mathemat…

 

by AEB Pupo – ‎Cited by 3 – ‎Related articles

Dec 9, 2011 – are connected to an electrical device that produces a direct current, … The tumor size determines how many needle electrodes are …. treatment of patients with various histological types of cancer in other hospitals of Sweden.

Electrochemical Therapy of Tumors – Hindawi

by L Jing-Hong – ‎2013 – ‎Cited by 5 – ‎Related articles

Apr 17, 2013 – Application of electric current for the tumor destruction has a long time history. … of this modality was initiated by the Swedish radiologist, Nordenstrom. … cancer patients with 26 tumors in which he used the “skinny needle” he …

Will Electricity Kill Cancer Cells | Articles | Information – MedFaxx

www.medfaxxinc.com/articles/cancer-and-functional-restoration.html

 

… in Stockholm,Sweden, Bjorn Nordenstrom, had discovered a way to kill cancer tumors with electricity. It was reported that by inserting a needle inside a tumor, …

Shattering Cancer With Resonant Frequencies

Oct 21, 2015 – Frequencies, known as oscillating pulsed electric field (OPEF) technology, destroyed an average of 25 to 42 percent of leukemia cells

Patents
Patent number: 9032964
Abstract: A scientific computer system with processor capable of recording, storing, and reprogramming the natural electrical signals of cancer cells as found in tumors of humans and animals. The reprogramming process is designed to create a confounding electrical signal for retransmission into a malignant tumor to damage or shut-down the cellular internal electrical communication system. Altering the electrical charge on the glycocalyx of the outer cell membrane is also part of the treatment by application of ions. The invention causes cancer cell death as a medical treatment using ultra-low voltage and amperage encoded signals which are reprogrammed from cancer cell communication signals.
Type: Grant
Filed: February 18, 2014
Date of Patent: May 19, 2015
Assignee: Neuro Code Teen Holdings; LLC
Inventors: Eleanor Schuler, James K. Poliner, Donald E. Nash
Publication number: 20140228910
Abstract: A scientific computer system with processor capable of recording, storing, and reprogramming the natural electrical signals of cancer cells as found in tumors of humans and animals. The reprogramming process is designed to create a confounding electrical signal for retransmission into a malignant tumor to damage or shut-down the cellular internal electrical communication system. Altering the electrical charge on the glycocalyx of the outer cell membrane is also part of the treatment by application of ions. The invention causes cancer cell death as a medical treatment using ultra-low voltage and amperage encoded signals which are reprogrammed from cancer cell communication signals.
Type: Application
Filed: February 18, 2014
Publication date: August 14, 2014
Applicant: Neuro Code Tech Holdings, LLC
Inventors: Eleanor Schuler, James K. Poliner, Donald E. Nash
Publication number: 20170266371
Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
Type: Application
Filed: March 15, 2017
Publication date: September 21, 2017
Applicant: CalXStars Business Accelerator, Inc.
Inventors: Howard J. Leonhardt, Jorge Genovese
Patent number: 6149575
Abstract: A radiation delivery catheter with inflatable chambers which provide a layer of radiation of minimum effective dose possible to be delivered as close as possible to the origin of disease within a blood vessel. The device can be centered within the true lumen of a vessel to provide even dispersion of the radiation agent to the outer wall of the vessel. The catheter comprises two central self centering balloons, one thin radiation agent inflatable chamber, and one radiation spread cloaking inflatable chamber with high strength properties resistant to rupture.
Type: Grant
Filed: July 7, 1998
Date of Patent: November 21, 2000
Assignee: World Medical Manufacturing Corporation
Inventor: Howard J. Leonhardt
Related Information from Independent Researchers:
source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845545/

The Bioelectric Code: Reprogramming Cancer

Frontiers | The Bioelectric Code: Reprogramming Cancer and Aging …
https://www.frontiersin.org/articles/10.3389/fcell.2018.00021 by BB Silver – ‎2018
Mar 6, 2018 – The Bioelectric CodeReprogramming Cancer and Aging From the Interface of Mechanical and Chemical Microenvironments. Brian B. Silver1 and Celeste M. Nelson1,2*. 1Department of Molecular Biology, Princeton University, Princeton, NJ, United States; 2Department of Chemical and Biological …

Micro Bioelectric Cancer Therapy Device 

No bigger than a postage stamp, the device contains electrodes and tiny channels embedded in a transparent polymer. It enables TTFields to be applied on cancer cells in a three-dimensional environment; conventional flat cell cultures are done on agar plates. It uses fewer reagents and facilities because of its small size, so costs can be cut down.

Singapore-made device to aid in developing cancer therapy …
www.straitstimes.com/…/spore-made-device-to-aid-in-developing-cancer-therapy

Dec 5, 2016 – About 10 years ago, an international team of researchers showed the therapy slowed the growth of a highly aggressive type of brain tumour called glioblastoma multiforme (GBM). The only side effect … Novocure is already conducting trials for other cancers, including lung, ovarian and pancreatic. Dr Kevin ..

Multiple Published Studies
Multiple Published Studies by researchers from around the globe have documented the ability of bioelectric therapy to slow or stop cancer tumor growth with less toxicity previously found with chemo and radiation therapies.

Here are just a few…

Brain Cancer Study 695 patients – https://academic.oup.com/neuro-oncology/article/18/suppl_6/i1/2543487

Skin Cancer – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119968/

Summary of clinical studies evaluating the efficacy of electromagnetic fields (EMF) as diagnostic or therapeutic modalities
Application
Study
Modality
Results
Diagnostics
Pearlman et al.[13]
Magnetoencephalography
Non-invasive modality for differentiating among neoplastic brain tissues, designed to be used in combination with CT and/or MRI

Vannelli et al.[14]
TRIMprob
Exploited tissue resonance differences between neoplastic and normal tissue, used in the diagnosis of prostate and rectal cancers

Barbault et al.[20]
TheraBionic
Identified a tumor-specific frequency signature in patients diagnosed with cancer
Therapeutics
Aaron et al.[16]
Electric fields and EMF to facilitate fracture healing
Suggested that EMF has efficacy similar to a graft in the treatment of nonunion fractures and spinal fusions

Pasche et al.[28]
LEET to treat physiologic insomnia
Demonstrated decreased sleep latency and increased sleep duration in patients treated with LEET in a double-blind cross-over study

Stupp et al.[23]
NovoTTF-100A
Delivery of electric fields rather than chemotherapy in patients with recurrent glioblastoma multiforme demonstrated efficacy comparable to chemotherapy regimens

Costa et al.[21]
TheraBionic
Amplitude-modulated RF EMF demonstrated safety and antitumor effects in patients with unresectable hepatocellular carcinoma
CT, computed tomography; MRI, magnetic resonance imaging; LEET, low-energy emission therapy; RF, radiofrequency.

Credit source:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845545/