9,707,403 Rapid destruction of malignant tumors by excitotoxicity and osmotic-shock medical tactics
9,636,507 Rapid destruction of malignant tumors by excitotoxicity and osmotic-shock medical tactics
9,492,478 Encoded bioelectronic method and system and calcium treatment for slaying cancer by rapid triggering of cellular apoptosis and karyorrhexis
9,440,083 Rapid destruction of malignant tumors by excitotoxicity and osmotic-shock medical tactics
9,295,835 Encoded bioelectronic method and system and calcium treatment for slaying cancer by rapid triggering of cellular apoptosis and karyorrhexis
9,032,964 Method and system for processing cancer cell electrical signals for medical therapy
8,831,738 System and method to elicit apoptosis in malignant tumor cells for medical treatment
3778-P15405.1US
8,656,930 Method and system for processing cancer cell electrical signals for medical therapy
8,315,712 Hybrid scientific computer system for processing cancer cell signals as medical therapy

Tumor therapy Patent number: 11185691 Abstract: Described are a system and method that “reads” cancer tumors real time and custom delivers individualized bioelectric therapy to the patient. For example, the system reads a cancer tumor, and based upon this read, delivers to the subject “a confounding signal” to jam communication within that tumor. A cancer tumor may change its communication patterns and the therapy is designed to change with these patterns, attempting to always jam the relevant communication signaling pathway. The described system includes parameters not tied to communication jamming, which should also be customized to induce apoptosis to the cancer tumor. Such parameters include signals for starving a cancer tumor of blood supply and signals for changing the cancer tumor’s surface proteins and/or charge so that the immune system attacks the cancer tumor. Type: Grant Filed: September 20, 2018 Date of Patent: November 30, 2021 Assignee: LEONHARDT VENTURES LLC Inventors: Howard J. Leonhardt, Jorge Genovese System and method for treating inflammation Patent number: 11110274 Abstract: Described is a low voltage, pulsed electrical stimulation device for reducing inflammation in a subject, which can be useful in the treatment of concussions, traumatic brain injury, cancer, and so forth. Type: Grant Filed: September 20, 2018 Date of Patent: September 7, 2021 Assignee: LEONHARDT VENTURES LLC Inventor: Howard J. Leonhardt BIOELECTRIC OPG TREATMENT OF CANCER Publication number: 20200330759 Abstract: Described is a method of treating a subject diagnosed with cancer, breast cancer, bone cancer, lung cancer, osteoporosis, multiple myeloma, and a combination of any thereof by applying a bioelectric signal or signals that upregulate the expression of Osteoprotegerin (“OPG”) and thus beneficially effect the subject’s OPG/RANKL/RANK pathway. Type: Application Filed: June 26, 2020 Publication date: October 22, 2020 Inventors: Howard J. Leonhardt, Jorge Genovese. KLOTHO MODULATION Publication number: 20200289826 Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells. Type: Application Filed: March 13, 2019 Publication date: September 17, 2020 Inventor: Howard J. Leonhardt Stimulator, pump and composition Patent number: 10646644 Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves. Type: Grant Filed: March 15, 2017 Date of Patent: May 12, 2020 Assignee: CalXStars Business Accelerator, Inc. Inventors: Howard J. Leonhardt, Jorge Genovese